SKP1P3

Across TCGA pan-cancer cohorts, SKP1P3 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated SKP1P3 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher SKP1P3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SKP1P3 expression acts as an unfavorable survival marker.

LUSC, PAAD, and CHOL are the cancer types where SKP1P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	II,III,IV	0.011	0.733	<.001	54	view →
PAAD	OS	Tertile	All	0.132	0.613	.002	45	view →
CHOL	DFS	Tertile	All	0.037	0.486	.001	18	view →
COAD	DFS	Tertile	All	0.241	0.793	.016	18	view →
KIRP	DFS	Tertile	All	0.178	0.829	<.001	18	view →
LIHC	OS	Tertile	All	0.031	0.775	<.001	18	view →
LUAD	DFS	Tertile	IV	0.333	0.671	.048	18	view →
HNSC	OS	Tertile	II,III,IV	0.526	0.760	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

SKP1P3–LUSC (OS)

Open the LUSC breakdown →