SKP1P2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SKP1P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,295 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SKP1P2-associated GO terms across cancer lineages are Rescue of stalled ribosome, Transcription by RNA polymerase III, and Translational elongation. Each is linked with SKP1P2 in more than 17 cancer types. Because this analysis shows association rather than direction, both SKP1P2-to-partner and partner-to-SKP1P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rescue of stalled ribosome grouped by SKP1P2-low versus SKP1P2-high in ACC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SKP1P2→partner) and Y-score (partner→SKP1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ACCRescue of stalled ribosome →+0.040+0.218<.001.002218
UCSTranscription by RNA polymerase III →+0.038+0.373<.001.001316
THYMTranslational elongation →+0.037+0.170<.001.005316
KICHPositive regulation of mRNA processing →+0.073+0.120<.001<.001316
ACCMitochondrial gene expression →+0.029+0.280<.001<.001315
STADAmino acid activation →+0.035+0.210.002.009117
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,295 associations by consensus.

Rescue of stalled ribosome by SKP1P2 expression — ACC

Box plot of Rescue of stalled ribosome in SKP1P2-low vs SKP1P2-high samples in ACC.

Explore this box plot interactively →

Exploration