Across TCGA patient cohorts, SKOR2 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SKOR2-associated genes across cancer lineages are MEK1, NF2, and beta-Catenin. Each is linked with SKOR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SKOR2-to-partner and partner-to-SKOR2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SKOR2→partner) and Y-score (partner→SKOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.479	+3.459	.009	.005	3	1
UCEC	NF2 →	+0.353	+2.321	.001	.035	3	1
UCEC	beta-Catenin →	+0.603	+3.000	.017	.036	3	1
UCEC	cIAP →	+0.149	+2.846	.030	.033	3	1
UCEC	4E-BP1 →	+0.445	+2.321	.001	.035	3	1
UCEC	14-3-3_beta →	-0.162	-2.301	.001	.034	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

SKOR2 survival (RNA) · tumor vs normal (RNA) · all SKOR2 data types