Across TCGA cell cohorts, SKOR2 mutation is significantly associated with the RNA expression of many other genes, with 54 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SKOR2-associated genes across cancer lineages are PRR23A, DAOA, and CTXN2. Each is linked with SKOR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SKOR2-to-partner and partner-to-SKOR2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SKOR2→partner) and Y-score (partner→SKOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	PRR23A →	+0.098	+4.228	<.001	.006	3	2
OESOPHAGUS	DAOA →	+0.062	+3.392	<.001	.007	3	1
OESOPHAGUS	CTXN2 →	+0.018	+3.392	.007	.007	3	1
OESOPHAGUS	PGA5 →	+0.094	+3.584	.006	.008	3	1
OESOPHAGUS	ELOA3CP →	+0.133	+3.652	<.001	.006	3	1
LUNG_SCLC	SPANXN1 →	+0.547	+3.624	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

Exploration

SKOR2 survival (RNA) · tumor vs normal (RNA) · all SKOR2 data types