Across TCGA pan-cancer cohorts, SKOR1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SKOR1 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher SKOR1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SKOR1 expression acts as an unfavorable survival marker.

ESCA, LUSC, and PRAD are the cancer types where SKOR1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Median	All	0.074	0.536	<.001	18	view →
LUSC	OS	Median	All	0.184	0.729	.001	9	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SKOR1 tumor-vs-normal RNA expression · all SKOR1 data types