SKIDA1

Across TCGA patient cohorts, SKIDA1 mutation is significantly associated with the RNA expression of many other genes, with 5,012 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SKIDA1-associated genes across cancer lineages are PES1, MAPK1, and SRRD. Each is linked with SKIDA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SKIDA1-to-partner and partner-to-SKIDA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PES1 grouped by SKIDA1-low versus SKIDA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SKIDA1→partner) and Y-score (partner→SKIDA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PES1 →	+0.438	+1.678	<.001	<.001	3	2
UCEC	MAPK1 →	+0.453	+1.874	<.001	.002	3	2
UCEC	SRRD →	+0.400	+1.678	<.001	<.001	3	2
UCEC	TFIP11 →	+0.426	+1.917	<.001	<.001	3	2
UCEC	GCAT →	+0.396	+2.579	.008	<.001	3	2
UCEC	SNU13 →	+0.240	+1.580	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,012 associations by consensus.

PES1 by SKIDA1 expression — UCEC

Explore this box plot interactively →