SKIDA1

Across TCGA patient cohorts, SKIDA1 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SKIDA1-associated genes across cancer lineages are ASNS, ATM, and EGFR_pY1068. Each is linked with SKIDA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SKIDA1-to-partner and partner-to-SKIDA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by SKIDA1-low versus SKIDA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SKIDA1→partner) and Y-score (partner→SKIDA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.417	+1.874	<.001	.002	3	3
UCEC	ATM →	-0.629	-1.857	<.001	<.001	3	3
COAD	EGFR_pY1068 →	-0.475	-3.169	.001	.017	3	2
COAD	INPP4B →	-0.411	-2.313	.014	.035	3	2
COAD	JNK_pT183_Y185 →	-0.279	-2.313	.017	.035	3	2
UCEC	MEK1 →	+0.458	+1.857	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

ASNS by SKIDA1 expression — UCEC

Explore this box plot interactively →