SKIDA1

Across TCGA cell cohorts, SKIDA1 mutation is significantly associated with the RNA expression of many other genes, with 275 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SKIDA1-associated genes across cancer lineages are GCAT, CBY1, and USP14. Each is linked with SKIDA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SKIDA1-to-partner and partner-to-SKIDA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GCAT grouped by SKIDA1-low versus SKIDA1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SKIDA1→partner) and Y-score (partner→SKIDA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GCAT →	+1.360	+3.169	<.001	.009	3	1
LARGE_INTESTINE	CBY1 →	+0.575	+3.451	.003	.002	3	1
LARGE_INTESTINE	USP14 →	+0.737	+3.237	.001	.003	3	1
LARGE_INTESTINE	CCNP →	+1.265	+3.364	.001	.002	3	1
LARGE_INTESTINE	MINPP1 →	+0.653	+3.169	.001	.009	3	1
LARGE_INTESTINE	GAR1 →	+0.559	+3.169	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 275 associations by consensus.

GCAT by SKIDA1 expression — LARGE_INTESTINE

Explore this box plot interactively →