SKAP2

Across TCGA cell cohorts, SKAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,947 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SKAP2-associated GO terms across cancer lineages are Endosomal transport, Regulation of cell-matrix adhesion, and Protein localization to membrane. Each is linked with SKAP2 in more than 12 cancer types. Because this analysis shows association rather than direction, both SKAP2-to-partner and partner-to-SKAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by SKAP2-low versus SKAP2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SKAP2→partner) and Y-score (partner→SKAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.075	+1.183	<.001	<.001	3	12
BONE	Regulation of cell-matrix adhesion →	+0.098	+1.649	.004	<.001	3	12
LUNG_NSCLC_LUSC	Protein localization to membrane →	+0.076	+1.347	.003	.002	3	11
BONE	Membrane fusion →	+0.049	+2.327	.001	<.001	1	13
BONE	Establishment of protein localization to plasma membrane →	+0.119	+2.886	<.001	<.001	3	11
LARGE_INTESTINE	Vesicle fusion →	+0.050	+1.023	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,947 associations by consensus.

Endosomal transport by SKAP2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →