Across TCGA patient cohorts, SIVA1 protein abundance is significantly associated with the protein abundance of many other proteins, with 14,401 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SIVA1-associated proteins across cancer lineages are UBR7, VEZF1, and RAD21. Each is linked with SIVA1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SIVA1-to-partner and partner-to-SIVA1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SIVA1→partner) and Y-score (partner→SIVA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UBR7 →	+0.451	+0.933	<.001	<.001	3	7
BRCA	VEZF1 →	+0.575	+0.935	<.001	<.001	3	7
GBM	RAD21 →	+0.228	+0.905	<.001	<.001	3	6
GBM	ACIN1 →	+0.283	+1.155	<.001	<.001	3	6
GBM	HNRNPK →	+0.340	+1.105	<.001	<.001	3	6
BRCA	KIAA1143 →	+0.376	+0.887	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,401 associations by consensus.

Exploration

SIVA1 survival (RNA) · tumor vs normal (RNA) · all SIVA1 data types