Across TCGA patient cohorts, SIVA1 mutation is significantly associated with the RNA expression of many other genes, with 390 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SIVA1-associated genes across cancer lineages are MIR1179, MTATP6P30, and LINC02164. Each is linked with SIVA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SIVA1-to-partner and partner-to-SIVA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SIVA1→partner) and Y-score (partner→SIVA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR1179 →	+1.171	+7.741	<.001	.009	3	2
COAD	MTATP6P30 →	+0.147	+7.741	<.001	.009	3	2
BLCA	LINC02164 →	+0.153	+7.640	<.001	.009	3	2
BLCA	ELOCP5 →	+0.239	+7.640	<.001	.009	3	2
SKCM	RNY4P18 →	+0.394	+5.199	<.001	.003	3	2
SKCM	RN7SKP188 →	+0.155	+5.328	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 390 associations by consensus.

Exploration

SIVA1 survival (RNA) · tumor vs normal (RNA) · all SIVA1 data types