Across TCGA cell cohorts, SIVA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,356 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SIVA1-associated GO terms across cancer lineages are Regulation of cell cycle checkpoint, Mitotic DNA replication, and Nuclear DNA replication. Each is linked with SIVA1 in more than 16 cancer types. Because this analysis shows association rather than direction, both SIVA1-to-partner and partner-to-SIVA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIVA1→partner) and Y-score (partner→SIVA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cell cycle checkpoint →	+0.116	+1.193	.008	.004	3	16
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA replication →	+0.183	+1.133	.002	.004	3	16
UPPER_AERODIGESTIVE_TRACT	Nuclear DNA replication →	+0.133	+1.296	.001	<.001	3	16
OESOPHAGUS	Mitotic DNA replication checkpoint signaling →	+0.167	+0.800	.001	.001	3	16
URINARY_TRACT	Regulation of DNA-templated DNA replication →	+0.107	+1.241	.002	<.001	2	17
LUNG_NSCLC_LUSC	Interstrand cross-link repair →	+0.100	+1.182	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,356 associations by consensus.

Exploration

SIVA1 survival (RNA) · tumor vs normal (RNA) · all SIVA1 data types