Across TCGA cell cohorts, SIVA1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SIVA1-associated genes across cancer lineages are CELA3A, CRNN, and SMCP. Each is linked with SIVA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SIVA1-to-partner and partner-to-SIVA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SIVA1→partner) and Y-score (partner→SIVA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CELA3A →	+0.090	+6.247	<.001	<.001	3	1
BLOOD_Lymphoma	CRNN →	+0.259	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	SMCP →	+0.030	+4.867	.001	.009	3	1
BLOOD_Lymphoma	MRGPRG →	+0.056	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	IFNA1 →	+0.154	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	USP17L4 →	+0.006	+5.209	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

SIVA1 survival (RNA) · tumor vs normal (RNA) · all SIVA1 data types