Across TCGA cell cohorts, SIRT7 RNA expression is significantly associated with the RNA expression of many other genes, with 9,655 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SIRT7-associated genes across cancer lineages are TEPSIN, HGS, and LRRC45. Each is linked with SIRT7 in more than 17 cancer types. Because this analysis shows association rather than direction, both SIRT7-to-partner and partner-to-SIRT7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SIRT7→partner) and Y-score (partner→SIRT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	TEPSIN →	+1.243	+1.029	<.001	<.001	3	18
URINARY_TRACT	HGS →	+0.808	+0.712	<.001	<.001	3	18
BREAST	LRRC45 →	+1.704	+1.328	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	GGA3 →	+1.445	+1.223	<.001	<.001	3	17
BONE	CCDC137 →	+0.961	+0.980	<.001	<.001	3	16
OESOPHAGUS	CSNK1D →	+1.139	+1.121	.002	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,655 associations by consensus.

Exploration

SIRT7 survival (RNA) · tumor vs normal (RNA) · all SIRT7 data types