SIRPG

Across TCGA patient cohorts, SIRPG RNA expression is significantly associated with the protein abundance of many other proteins, with 17,136 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SIRPG-associated proteins across cancer lineages are PSMB10, PTPN6, and PTPN7. Each is linked with SIRPG in more than 9 cancer types. Because this analysis shows association rather than direction, both SIRPG-to-partner and partner-to-SIRPG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIRPG versus PSMB10 in HNSC, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SIRPG→partner) and Y-score (partner→SIRPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PSMB10 →	+0.598	+1.081	<.001	<.001	3	10
GBM	PTPN6 →	+0.607	+0.448	<.001	<.001	3	10
BRCA	PTPN7 →	+0.615	+1.284	<.001	<.001	3	10
BRCA	RAC2 →	+0.958	+1.417	<.001	<.001	3	10
OV	ARHGAP45 →	+0.638	+1.062	<.001	<.001	3	10
OV	CASP1 →	+0.551	+0.647	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,136 associations by consensus.

SIRPG vs PSMB10 — HNSC

Explore this scatter interactively →