SIRPG

Across TCGA patient cohorts, SIRPG protein abundance is significantly associated with the RNA expression of many other genes, with 593 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SIRPG-associated genes across cancer lineages are PANX1, CBL, and CD81. Each is linked with SIRPG in more than 1 cancer types. Because this analysis shows association rather than direction, both SIRPG-to-partner and partner-to-SIRPG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIRPG versus PANX1 in LSCC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SIRPG→partner) and Y-score (partner→SIRPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PANX1 →	-0.762	-0.961	.006	.009	3	1
LSCC	CBL →	-0.583	-0.961	.005	.009	3	1
LSCC	CD81 →	-0.468	-0.961	<.001	.009	3	1
LSCC	ATP6V0B →	-0.578	-0.961	<.001	.009	3	1
LSCC	MTHFD1L →	-0.802	-0.961	.002	.009	3	1
LSCC	DMGDH →	-1.275	-0.961	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 593 associations by consensus.

SIRPG vs PANX1 — LSCC

Explore this scatter interactively →