SIRPG

Across TCGA cell cohorts, SIRPG RNA expression is significantly associated with the go_rna of many other GO terms, with 843 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SIRPG-associated GO terms across cancer lineages are T-helper 17 type immune response, Leukocyte cell-cell adhesion, and T-helper 17 cell differentiation. Each is linked with SIRPG in more than 6 cancer types. Because this analysis shows association rather than direction, both SIRPG-to-partner and partner-to-SIRPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T-helper 17 type immune response grouped by SIRPG-low versus SIRPG-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIRPG→partner) and Y-score (partner→SIRPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	T-helper 17 type immune response →	+0.101	+0.099	.001	.003	3	7
BLOOD_Leukemia	Leukocyte cell-cell adhesion →	+0.118	+1.096	<.001	.005	3	6
BREAST	T-helper 17 cell differentiation →	+0.128	+0.603	<.001	.003	3	6
BREAST	Regulation of defense response to virus by host →	+0.085	+0.392	<.001	.007	3	6
LUNG_NSCLC_LUAD	Complement-mediated synapse pruning →	+0.844	+0.196	.001	.001	3	6
LUNG_NSCLC_LUAD	Positive regulation of complement activation →	+1.065	+0.181	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 843 associations by consensus.

T-helper 17 type immune response by SIRPG expression — STOMACH

Explore this box plot interactively →