SIRPD

Across TCGA cell cohorts, SIRPD RNA expression is significantly associated with the go_rna of many other GO terms, with 1,646 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SIRPD-associated GO terms across cancer lineages are Positive regulation of calcium ion transport into cytosol, Response to angiotensin, and Regulation of chemokine production. Each is linked with SIRPD in more than 3 cancer types. Because this analysis shows association rather than direction, both SIRPD-to-partner and partner-to-SIRPD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of calcium ion transport into cytosol grouped by SIRPD-low versus SIRPD-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIRPD→partner) and Y-score (partner→SIRPD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of calcium ion transport into cytosol →	+0.211	+0.117	<.001	.002	3	4
BLOOD_Leukemia	Response to angiotensin →	+0.091	+0.496	<.001	<.001	3	4
BLOOD_Leukemia	Regulation of chemokine production →	+0.076	+0.644	<.001	<.001	3	4
URINARY_TRACT	Endocytosis involved in viral entry into host cell →	+0.126	+0.119	<.001	.007	3	3
URINARY_TRACT	Receptor-mediated endocytosis of virus by host cell →	+0.143	+0.119	.002	.007	3	3
BREAST	Negative regulation of cardiac muscle adaptation →	+0.179	+0.176	.004	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,646 associations by consensus.

Positive regulation of calcium ion transport into cytosol by SIRPD expression — OVARY

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