Across TCGA cell cohorts, SIRPB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,567 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SIRPB2-associated GO terms across cancer lineages are Cell-substrate junction assembly, Positive regulation of ATP biosynthetic process, and Antimicrobial peptide production. Each is linked with SIRPB2 in more than 7 cancer types. Because this analysis shows association rather than direction, both SIRPB2-to-partner and partner-to-SIRPB2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIRPB2→partner) and Y-score (partner→SIRPB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Cell-substrate junction assembly →	+0.123	+0.644	.002	.009	3	8
BREAST	Positive regulation of ATP biosynthetic process →	+0.153	+0.607	<.001	.008	3	7
BREAST	Antimicrobial peptide production →	+1.567	+0.934	<.001	.007	3	7
BREAST	Antimicrobial peptide biosynthetic process →	+1.567	+0.934	<.001	.007	3	7
BREAST	Antibacterial peptide production →	+1.567	+0.934	<.001	.007	3	7
BREAST	Antibacterial peptide biosynthetic process →	+1.567	+0.934	<.001	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,567 associations by consensus.

Exploration

SIRPB2 survival (RNA) · tumor vs normal (RNA) · all SIRPB2 data types