SIRPB1

Across TCGA cell cohorts, SIRPB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,893 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SIRPB1-associated GO terms across cancer lineages are Monocyte extravasation, Endocytosis involved in viral entry into host cell, and Receptor-mediated endocytosis of virus by host cell. Each is linked with SIRPB1 in more than 13 cancer types. Because this analysis shows association rather than direction, both SIRPB1-to-partner and partner-to-SIRPB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocyte extravasation grouped by SIRPB1-low versus SIRPB1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIRPB1→partner) and Y-score (partner→SIRPB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Monocyte extravasation →	+1.638	+1.555	<.001	<.001	3	14
LIVER	Endocytosis involved in viral entry into host cell →	+0.169	+1.545	.005	.005	3	11
BREAST	Receptor-mediated endocytosis of virus by host cell →	+0.202	+1.258	<.001	<.001	3	10
CNS	Regulation of hemostasis →	+0.144	+0.886	<.001	<.001	3	9
CNS	Extracellular matrix organization →	+0.102	+0.997	.002	.005	3	9
CNS	Extracellular structure organization →	+0.103	+0.997	.002	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,893 associations by consensus.

Monocyte extravasation by SIRPB1 expression — URINARY_TRACT

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