SIPA1L3

Across TCGA patient cohorts, SIPA1L3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,426 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SIPA1L3-associated proteins across cancer lineages are SIPA1L3_T1703, SIPA1L3_S1364, and SIPA1L3_S1544. Each is linked with SIPA1L3 in more than 6 cancer types. Because this analysis shows association rather than direction, both SIPA1L3-to-partner and partner-to-SIPA1L3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIPA1L3 versus SIPA1L3_T1703 in HNSC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SIPA1L3→partner) and Y-score (partner→SIPA1L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SIPA1L3_T1703 →	+0.568	+1.054	<.001	<.001	3	7
HNSC	SIPA1L3_S1364 →	+0.686	+0.987	<.001	<.001	3	6
CCRCC	SIPA1L3_S1544 →	+0.668	+0.637	<.001	<.001	3	6
BRCA	SIPA1L3_S100 →	+1.030	+0.819	.001	.002	3	5
OV	SNRPD3 →	+0.287	+1.071	.003	.003	2	6
GBM	SUPT5H →	+0.211	+0.560	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,426 associations by consensus.

SIPA1L3 vs SIPA1L3_T1703 — HNSC

Explore this scatter interactively →