SIPA1L3

Across TCGA cell cohorts, SIPA1L3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,406 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SIPA1L3-associated GO terms across cancer lineages are Cytosolic transport, Post-Golgi vesicle-mediated transport, and Vesicle-mediated transport to the plasma membrane. Each is linked with SIPA1L3 in more than 14 cancer types. Because this analysis shows association rather than direction, both SIPA1L3-to-partner and partner-to-SIPA1L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by SIPA1L3-low versus SIPA1L3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIPA1L3→partner) and Y-score (partner→SIPA1L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.069	+0.980	<.001	.001	3	15
BREAST	Post-Golgi vesicle-mediated transport →	+0.076	+1.316	<.001	<.001	3	13
LARGE_INTESTINE	Vesicle-mediated transport to the plasma membrane →	+0.071	+1.446	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.054	+1.095	.009	.002	3	12
KIDNEY	Negative regulation of calcium ion export across plasma membrane →	+0.076	+1.565	<.001	.001	3	12
STOMACH	Endocytic recycling →	+0.071	+1.810	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,406 associations by consensus.

Cytosolic transport by SIPA1L3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →