SIPA1L2

Across TCGA patient cohorts, SIPA1L2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,035 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SIPA1L2-associated proteins across cancer lineages are SIPA1L2_S1461, SIPA1L2_S1488, and SIPA1L2_S1244. Each is linked with SIPA1L2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SIPA1L2-to-partner and partner-to-SIPA1L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIPA1L2 versus SIPA1L2_S1461 in BRCA, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SIPA1L2→partner) and Y-score (partner→SIPA1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SIPA1L2_S1461 →	+0.700	+1.128	<.001	<.001	3	10
LUAD	SIPA1L2_S1488 →	+0.878	+1.541	<.001	<.001	3	9
LSCC	SIPA1L2_S1244 →	+0.854	+1.213	<.001	<.001	3	8
LSCC	SIPA1L2_S1478 →	+1.005	+1.279	<.001	<.001	3	8
LSCC	SIPA1L2_S148 →	+0.877	+1.139	<.001	<.001	3	8
LSCC	SIPA1L2_S1549 →	+1.060	+1.171	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,035 associations by consensus.

SIPA1L2 vs SIPA1L2_S1461 — BRCA

Explore this scatter interactively →