SIPA1L2

Across TCGA cell cohorts, SIPA1L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,198 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SIPA1L2-associated GO terms across cancer lineages are Aerobic respiration, Regulation of syncytium formation by plasma membrane fusion, and Oxidative phosphorylation. Each is linked with SIPA1L2 in more than 11 cancer types. Because this analysis shows association rather than direction, both SIPA1L2-to-partner and partner-to-SIPA1L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by SIPA1L2-low versus SIPA1L2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIPA1L2→partner) and Y-score (partner→SIPA1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Aerobic respiration →	+0.088	+1.706	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.099	+1.663	<.001	<.001	3	12
OESOPHAGUS	Oxidative phosphorylation →	+0.130	+1.978	<.001	<.001	3	12
OESOPHAGUS	Regulation of myoblast fusion →	+0.117	+1.727	<.001	.003	3	12
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.135	+1.727	<.001	.003	3	12
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.105	+1.810	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,198 associations by consensus.

Aerobic respiration by SIPA1L2 expression — OESOPHAGUS

Explore this box plot interactively →