Across TCGA patient cohorts, SIPA1L1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,825 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SIPA1L1-associated genes across cancer lineages are RDH11, ATP6V1D, and EIF2B2. Each is linked with SIPA1L1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SIPA1L1-to-partner and partner-to-SIPA1L1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SIPA1L1→partner) and Y-score (partner→SIPA1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RDH11 →	+0.572	+0.371	<.001	<.001	3	7
OV	ATP6V1D →	+0.552	+0.385	<.001	<.001	3	6
LUAD	EIF2B2 →	+0.539	+0.324	<.001	<.001	3	6
LUAD	ERG28 →	+0.630	+0.315	<.001	<.001	3	6
LUAD	SNW1 →	+0.538	+0.338	<.001	<.001	3	5
COAD	ERH →	+0.679	+0.392	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,825 associations by consensus.

Exploration

SIPA1L1 survival (RNA) · tumor vs normal (RNA) · all SIPA1L1 data types