Across TCGA cell cohorts, SIPA1L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,935 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SIPA1L1-associated GO terms across cancer lineages are Positive regulation of lymphoid progenitor cell differentiation, Positive regulation of canonical Wnt signaling pathway, and Regulation of ubiquitin-dependent protein catabolic process. Each is linked with SIPA1L1 in more than 10 cancer types. Because this analysis shows association rather than direction, both SIPA1L1-to-partner and partner-to-SIPA1L1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIPA1L1→partner) and Y-score (partner→SIPA1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of lymphoid progenitor cell differentiation →	+0.102	+0.571	<.001	.003	3	11
PANCREAS	Positive regulation of canonical Wnt signaling pathway →	+0.048	+1.503	<.001	<.001	3	10
KIDNEY	Regulation of ubiquitin-dependent protein catabolic process →	+0.068	+1.268	<.001	.001	3	10
BLOOD_Leukemia	Positive regulation of mRNA metabolic process →	+0.043	+1.260	<.001	<.001	3	9
URINARY_TRACT	Protein catabolic process at synapse →	+0.129	+0.939	.001	.003	2	10
URINARY_TRACT	Protein catabolic process at postsynapse →	+0.129	+0.939	.001	.003	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,935 associations by consensus.

Exploration

SIPA1L1 survival (RNA) · tumor vs normal (RNA) · all SIPA1L1 data types