SIPA1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SIPA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,258 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SIPA1-associated GO terms across cancer lineages are Response to water deprivation, Response to water, and Cellular response to water stimulus. Each is linked with SIPA1 in more than 17 cancer types. Because this analysis shows association rather than direction, both SIPA1-to-partner and partner-to-SIPA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIPA1→partner) and Y-score (partner→SIPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHResponse to water deprivation →+0.232+1.183<.001<.001318
LUNG_NSCLC_LUSCResponse to water →+0.196+1.297.004.004314
LUNG_SCLCCellular response to water stimulus →+0.254+1.478.009<.001313
STOMACHProlactin signaling pathway →+0.174+0.966.008<.00139
BONEResponse to hypobaric hypoxia →+0.152+0.992.002.00629
KIDNEYRegulation of pattern recognition receptor signaling pathway →+0.054+0.984.004.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,258 associations by consensus.

Exploration