SIN3B

Across TCGA patient cohorts, SIN3B protein abundance is significantly associated with the RNA expression of many other genes, with 15,657 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SIN3B-associated genes across cancer lineages are ZNF286B, FOXO3B, and C1orf112. Each is linked with SIN3B in more than 8 cancer types. Because this analysis shows association rather than direction, both SIN3B-to-partner and partner-to-SIN3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIN3B versus ZNF286B in GBM, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SIN3B→partner) and Y-score (partner→SIN3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZNF286B →	+0.893	+0.272	<.001	<.001	3	9
HNSC	FOXO3B →	+0.674	+0.236	.002	<.001	3	6
HNSC	C1orf112 →	+0.789	+0.313	<.001	<.001	3	6
GBM	CCNB1IP1 →	+0.749	+0.336	<.001	<.001	3	6
HNSC	CCDC77 →	+0.771	+0.255	<.001	<.001	3	6
HNSC	SNHG30 →	+0.576	+0.183	.007	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,657 associations by consensus.

SIN3B vs ZNF286B — GBM

Explore this scatter interactively →