SIN3B

Across TCGA patient cohorts, SIN3B protein abundance is significantly associated with the protein abundance of many other proteins, with 23,423 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SIN3B-associated proteins across cancer lineages are SUPT6H, DHX9, and SNRNP200. Each is linked with SIN3B in more than 7 cancer types. Because this analysis shows association rather than direction, both SIN3B-to-partner and partner-to-SIN3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIN3B versus SUPT6H in GBM, with a Pearson correlation of 0.69.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SIN3B→partner) and Y-score (partner→SIN3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SUPT6H →	+0.261	+0.304	<.001	<.001	3	8
HNSC	DHX9 →	+0.291	+0.323	<.001	<.001	3	8
GBM	SNRNP200 →	+0.273	+0.301	<.001	<.001	3	8
LSCC	AQR →	+0.313	+0.209	<.001	<.001	3	8
GBM	NXF1 →	+0.323	+0.310	<.001	<.001	3	8
GBM	CTR9 →	+0.239	+0.282	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,423 associations by consensus.

SIN3B vs SUPT6H — GBM

Explore this scatter interactively →