SIL1

Across TCGA cell cohorts, SIL1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,590 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SIL1-associated genes across cancer lineages are FERMT1, SYNRG, and ARHGEF26. Each is linked with SIL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SIL1-to-partner and partner-to-SIL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIL1 versus FERMT1 in BREAST, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SIL1→partner) and Y-score (partner→SIL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	FERMT1 →	-1.705	-0.829	<.001	.001	3	4
LUNG_NSCLC_LUSC	SYNRG →	+0.865	+1.976	.007	.003	3	4
LARGE_INTESTINE	ARHGEF26 →	+1.146	+0.779	<.001	.003	3	4
PANCREAS	NELFE →	+1.085	+1.221	.009	.008	3	4
URINARY_TRACT	GPS2 →	+1.085	+1.335	<.001	.007	3	4
STOMACH	ENO2 →	+2.610	+0.801	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,590 associations by consensus.

SIL1 vs FERMT1 — BREAST

Explore this scatter interactively →