SIGMAR1

Across TCGA patient cohorts, SIGMAR1 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SIGMAR1-associated genes across cancer lineages are Mesangial cells. Each is linked with SIGMAR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SIGMAR1-to-partner and partner-to-SIGMAR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesangial cells grouped by SIGMAR1-low versus SIGMAR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SIGMAR1→partner) and Y-score (partner→SIGMAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Mesangial cells →	-0.055	-3.159	.010	.020	1	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Mesangial cells by SIGMAR1 expression — UCEC

Explore this box plot interactively →