SIGLEC7

Across TCGA patient cohorts, SIGLEC7 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,419 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SIGLEC7-associated proteins across cancer lineages are MYO1F, MYO1G, and NCF1. Each is linked with SIGLEC7 in more than 9 cancer types. Because this analysis shows association rather than direction, both SIGLEC7-to-partner and partner-to-SIGLEC7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIGLEC7 versus MYO1F in GBM, with a Pearson correlation of 0.79.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SIGLEC7→partner) and Y-score (partner→SIGLEC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MYO1F →	+0.748	+1.067	<.001	<.001	3	10
GBM	MYO1G →	+0.721	+1.038	<.001	<.001	3	10
GBM	NCF1 →	+0.832	+0.976	<.001	<.001	3	10
GBM	NCF2 →	+0.885	+0.980	<.001	<.001	3	10
GBM	NCF4 →	+0.801	+1.017	<.001	<.001	3	10
GBM	ARHGAP30 →	+0.774	+1.039	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,419 associations by consensus.

SIGLEC7 vs MYO1F — GBM

Explore this scatter interactively →