SIGLEC5

Across TCGA patient cohorts, SIGLEC5 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,777 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SIGLEC5-associated proteins across cancer lineages are WIPF1, FMNL1, and MYO1F. Each is linked with SIGLEC5 in more than 7 cancer types. Because this analysis shows association rather than direction, both SIGLEC5-to-partner and partner-to-SIGLEC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIGLEC5 versus WIPF1 in OV, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SIGLEC5→partner) and Y-score (partner→SIGLEC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	WIPF1 →	+0.360	+0.105	<.001	.008	3	8
COAD	FMNL1 →	+0.423	+0.156	<.001	<.001	3	8
GBM	MYO1F →	+0.471	+0.112	<.001	.003	3	8
GBM	WAS →	+0.434	+0.140	<.001	<.001	3	7
LSCC	ARHGAP4 →	+0.360	+0.164	<.001	<.001	3	7
BRCA	ARHGAP45 →	+0.379	+0.118	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,777 associations by consensus.

SIGLEC5 vs WIPF1 — OV

Explore this scatter interactively →