SIGLEC5

Across TCGA patient cohorts, SIGLEC5 protein abundance is significantly associated with the RNA expression of many other genes, with 297 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SIGLEC5-associated genes across cancer lineages are LINC00211, STMN2, and NCS1. Each is linked with SIGLEC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SIGLEC5-to-partner and partner-to-SIGLEC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIGLEC5 versus LINC00211 in PDAC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SIGLEC5→partner) and Y-score (partner→SIGLEC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	LINC00211 →	+0.375	+0.349	.005	.004	2	2
GBM	STMN2 →	-2.492	-0.460	.005	.002	3	1
GBM	NCS1 →	-1.175	-0.498	.002	.006	3	1
GBM	ANAPC15 →	-0.571	-0.555	.002	.008	3	1
GBM	MCM9 →	-0.330	-0.468	.002	.002	3	1
GBM	MTRF1L →	-0.364	-0.483	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 297 associations by consensus.

SIGLEC5 vs LINC00211 — PDAC

Explore this scatter interactively →