SIGLEC20P

Across TCGA patient cohorts, SIGLEC20P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,745 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SIGLEC20P-associated GO terms across cancer lineages are Regulation of actin filament organization, Positive regulation of proteasomal protein catabolic process, and Respiratory system development. Each is linked with SIGLEC20P in more than 15 cancer types. Because this analysis shows association rather than direction, both SIGLEC20P-to-partner and partner-to-SIGLEC20P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of actin filament organization grouped by SIGLEC20P-low versus SIGLEC20P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIGLEC20P→partner) and Y-score (partner→SIGLEC20P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of actin filament organization →	+0.057	+0.143	<.001	<.001	3	16
ESCA	Positive regulation of proteasomal protein catabolic process →	+0.074	+0.152	<.001	.004	3	16
STAD	Respiratory system development →	+0.050	+0.131	<.001	<.001	3	16
STAD	Establishment of protein localization to membrane →	+0.065	+0.147	<.001	<.001	3	16
ESCA	Regulation of DNA repair →	+0.070	+0.135	<.001	<.001	3	16
STAD	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.055	+0.170	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,745 associations by consensus.

Regulation of actin filament organization by SIGLEC20P expression — STAD

Explore this box plot interactively →