SIGLEC10

Across TCGA patient cohorts, SIGLEC10 RNA expression is significantly associated with the RNA expression of many other genes, with 16,636 significant associations in total. UVM shows the largest number of these associations.

The most reproducible SIGLEC10-associated genes across cancer lineages are VSIG4, FCER1G, and MNDA. Each is linked with SIGLEC10 in more than 33 cancer types. Because this analysis shows association rather than direction, both SIGLEC10-to-partner and partner-to-SIGLEC10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIGLEC10 versus VSIG4 in BLCA, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SIGLEC10→partner) and Y-score (partner→SIGLEC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	VSIG4 →	+2.842	+1.988	<.001	<.001	3	34
BLCA	FCER1G →	+2.732	+2.011	<.001	<.001	3	34
BLCA	MNDA →	+2.246	+2.025	<.001	<.001	3	34
LAML	CCR1 →	+1.840	+1.236	<.001	<.001	3	34
BLCA	CYBB →	+2.694	+2.026	<.001	<.001	3	34
LAML	SIGLEC7 →	+1.947	+1.527	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,636 associations by consensus.

SIGLEC10 vs VSIG4 — BLCA

Explore this scatter interactively →