SIDT2

Across TCGA patient cohorts, SIDT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,456 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SIDT2-associated proteins across cancer lineages are YME1L1, DNMT1_S127, and UTRN. Each is linked with SIDT2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SIDT2-to-partner and partner-to-SIDT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SIDT2 versus YME1L1 in BRCA, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SIDT2→partner) and Y-score (partner→SIDT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	YME1L1 →	-0.317	-0.568	<.001	<.001	3	5
BRCA	DNMT1_S127 →	-0.590	-0.500	<.001	<.001	3	5
BRCA	UTRN →	+0.302	+0.536	<.001	.003	3	4
PDAC	UTRN_S1866 →	+1.060	+0.329	<.001	<.001	3	4
HNSC	VPS26B →	+0.238	+0.678	<.001	<.001	3	4
BRCA	MYLK →	+0.443	+0.644	.004	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,456 associations by consensus.

SIDT2 vs YME1L1 — BRCA

Explore this scatter interactively →