SIDT1-AS1

Across TCGA pan-cancer cohorts, SIDT1-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated SIDT1-AS1 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher SIDT1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SIDT1-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and HNSC show a favorable association.

OV, CHOL, and KIRC are the cancer types where SIDT1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Tertile	II,III,IV	0.454	0.351	.005	54	view →
CHOL	OS	Tertile	IV	0.024	0.732	.014	36	view →
KIRC	DFS	Quartile	All	0.729	0.825	.001	27	view →
HNSC	DFS	Quartile	All	0.750	0.590	.004	25	view →
LIHC	OS	Tertile	All	0.719	0.484	.014	24	view →
DLBC	DFS	Quartile	III,IV	0.074	0.984	.008	23	view →
BLCA	OS	Median	All	0.483	0.372	.020	21	view →
SKCM	DFS	Tertile	All	0.805	0.584	.004	21	view →
ACC	DFS	Tertile	III,IV	0.051	0.380	.001	18	view →
READ	OS	Quartile	III,IV	0.939	0.334	.018	18	view →
BRCA	DFS	Tertile	III,IV	0.675	0.451	.013	17	view →
ESCA	DFS	Median	All	0.447	0.926	.004	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

SIDT1-AS1–OV (DFS)

Open the OV breakdown →