SIAH1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SIAH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,557 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SIAH1-associated proteins across cancer lineages are PSME2, FTO, and ADGRG1. Each is linked with SIAH1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SIAH1-to-partner and partner-to-SIAH1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SIAH1→partner) and Y-score (partner→SIAH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCPSME2 →-0.309-0.368<.001<.00135
GBMFTO →+0.344+0.303<.001<.00135
LSCCADGRG1 →+0.510+0.355<.001.00634
CCRCCARID3A_S119 →-0.629-0.327.004.00334
GBMARL2BP →+0.285+0.345<.001<.00134
GBMPTPRC_S994 →-0.742-0.277<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,557 associations by consensus.

Exploration