Across TCGA cell cohorts, SIAH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,162 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SIAH1-associated GO terms across cancer lineages are Chemotaxis, Regulation of G0 to G1 transition, and Amyloid fibril formation. Each is linked with SIAH1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SIAH1-to-partner and partner-to-SIAH1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIAH1→partner) and Y-score (partner→SIAH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Chemotaxis →	-0.075	-0.762	<.001	<.001	3	10
OVARY	Regulation of G0 to G1 transition →	+0.133	+0.968	<.001	<.001	3	10
URINARY_TRACT	Amyloid fibril formation →	+0.147	+0.811	<.001	.006	3	10
SOFT_TISSUE	Epigenetic regulation of gene expression →	+0.057	+0.542	<.001	<.001	3	10
LARGE_INTESTINE	Taxis →	-0.075	-0.762	<.001	<.001	3	10
OVARY	Negative regulation of gene expression, epigenetic →	+0.058	+0.470	<.001	.009	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,162 associations by consensus.

Exploration

SIAH1 survival (RNA) · tumor vs normal (RNA) · all SIAH1 data types