SIAE

Across TCGA cell cohorts, SIAE RNA expression is significantly associated with the go_rna of many other GO terms, with 4,837 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SIAE-associated GO terms across cancer lineages are Lipid oxidation, Fatty acid beta-oxidation, and Fatty acid oxidation. Each is linked with SIAE in more than 14 cancer types. Because this analysis shows association rather than direction, both SIAE-to-partner and partner-to-SIAE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipid oxidation grouped by SIAE-low versus SIAE-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIAE→partner) and Y-score (partner→SIAE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Lipid oxidation →	+0.079	+1.018	.009	.004	2	15
STOMACH	Fatty acid beta-oxidation →	+0.090	+1.575	.001	.001	3	14
OESOPHAGUS	Fatty acid oxidation →	+0.073	+1.017	.003	.002	2	14
OVARY	Monocarboxylic acid catabolic process →	+0.064	+1.248	.002	.001	2	14
OVARY	Fatty acid catabolic process →	+0.072	+1.266	.001	<.001	3	13
SOFT_TISSUE	Lipid catabolic process →	+0.048	+1.483	<.001	<.001	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,837 associations by consensus.

Lipid oxidation by SIAE expression — KIDNEY

Explore this box plot interactively →