Across TCGA patient cohorts, SHTN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,488 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SHTN1-associated proteins across cancer lineages are SHTN1_S506, SHTN1_S494, and MSN. Each is linked with SHTN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SHTN1-to-partner and partner-to-SHTN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SHTN1→partner) and Y-score (partner→SHTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SHTN1_S506 →	+0.879	+0.582	<.001	<.001	3	7
UCEC	SHTN1_S494 →	+0.750	+0.484	<.001	<.001	3	6
GBM	MSN →	-0.387	-0.738	<.001	<.001	3	5
BRCA	SEC23IP →	+0.215	+0.442	<.001	<.001	3	5
LSCC	CACYBP →	+0.352	+0.740	<.001	<.001	3	5
GBM	ZNF318_S69 →	+0.940	+1.240	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,488 associations by consensus.

Exploration

SHTN1 survival (RNA) · tumor vs normal (RNA) · all SHTN1 data types