Across TCGA cell cohorts, SHTN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,576 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SHTN1-associated GO terms across cancer lineages are Cytoplasmic actin-based contraction involved in cell motility, Cdc42 protein signal transduction, and Organelle localization by membrane tethering. Each is linked with SHTN1 in more than 15 cancer types. Because this analysis shows association rather than direction, both SHTN1-to-partner and partner-to-SHTN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHTN1→partner) and Y-score (partner→SHTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Cytoplasmic actin-based contraction involved in cell motility →	+1.181	+2.798	<.001	<.001	3	16
BONE	Cdc42 protein signal transduction →	+1.335	+2.099	<.001	<.001	3	13
LUNG_SCLC	Organelle localization by membrane tethering →	+0.080	+1.535	<.001	<.001	3	12
OVARY	Regulation of myoblast fusion →	+0.133	+1.786	<.001	<.001	3	11
STOMACH	Post-Golgi vesicle-mediated transport →	+0.081	+1.781	.003	.002	3	11
OVARY	Vacuolar transport →	+0.068	+1.928	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,576 associations by consensus.

Exploration

SHTN1 survival (RNA) · tumor vs normal (RNA) · all SHTN1 data types