SHROOM3

Across TCGA patient cohorts, SHROOM3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,086 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SHROOM3-associated proteins across cancer lineages are SHROOM3_S1173, SHROOM3_S1221, and SHROOM3_S285. Each is linked with SHROOM3 in more than 8 cancer types. Because this analysis shows association rather than direction, both SHROOM3-to-partner and partner-to-SHROOM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SHROOM3 versus SHROOM3_S1173 in OV, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SHROOM3→partner) and Y-score (partner→SHROOM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SHROOM3_S1173 →	+1.446	+1.183	<.001	<.001	3	9
CCRCC	SHROOM3_S1221 →	+0.737	+1.531	<.001	<.001	3	9
BRCA	SHROOM3_S285 →	+1.991	+1.458	<.001	<.001	3	9
OV	SHROOM3_S664 →	+0.994	+1.097	<.001	<.001	3	9
CCRCC	SHROOM3_S403 →	+1.150	+1.457	<.001	<.001	3	8
BRCA	SHROOM3_S439 →	+0.849	+0.881	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,086 associations by consensus.

SHROOM3 vs SHROOM3_S1173 — OV

Explore this scatter interactively →