SHROOM3

Across TCGA cell cohorts, SHROOM3 RNA expression is significantly associated with the RNA expression of many other genes, with 9,583 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SHROOM3-associated genes across cancer lineages are RAB11FIP1, KRT8, and LLGL2. Each is linked with SHROOM3 in more than 9 cancer types. Because this analysis shows association rather than direction, both SHROOM3-to-partner and partner-to-SHROOM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SHROOM3 versus RAB11FIP1 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.59.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SHROOM3→partner) and Y-score (partner→SHROOM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	RAB11FIP1 →	+1.950	+1.160	<.001	.001	3	10
LUNG_SCLC	KRT8 →	+3.951	+2.261	<.001	<.001	3	10
STOMACH	LLGL2 →	+3.376	+2.007	<.001	.001	3	10
STOMACH	CGN →	+2.329	+1.562	.002	.002	2	10
BREAST	CACFD1 →	+1.383	+1.533	.001	<.001	2	10
STOMACH	SPINT1 →	+4.110	+1.881	<.001	.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,583 associations by consensus.

SHROOM3 vs RAB11FIP1 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →