SHROOM3

Across TCGA cell cohorts, SHROOM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,989 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SHROOM3-associated GO terms across cancer lineages are Regulation of myoblast fusion, Actomyosin structure organization, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with SHROOM3 in more than 9 cancer types. Because this analysis shows association rather than direction, both SHROOM3-to-partner and partner-to-SHROOM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by SHROOM3-low versus SHROOM3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHROOM3→partner) and Y-score (partner→SHROOM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of myoblast fusion →	+0.076	+1.607	<.001	<.001	3	10
OESOPHAGUS	Actomyosin structure organization →	+0.110	+1.772	.005	.002	3	10
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.075	+1.525	<.001	<.001	3	10
OVARY	Vacuolar transport →	+0.052	+2.229	<.001	<.001	3	10
LARGE_INTESTINE	Glycerophospholipid biosynthetic process →	+0.034	+1.503	<.001	.001	3	10
BLOOD_Myeloma	Regulation of amyloid fibril formation →	+0.139	+2.280	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,989 associations by consensus.

Regulation of myoblast fusion by SHROOM3 expression — OVARY

Explore this box plot interactively →