SHROOM2

Across TCGA patient cohorts, SHROOM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,233 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SHROOM2-associated proteins across cancer lineages are SHROOM2_S1297, SHROOM2_S313, and SHROOM2_S413. Each is linked with SHROOM2 in more than 8 cancer types. Because this analysis shows association rather than direction, both SHROOM2-to-partner and partner-to-SHROOM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SHROOM2 versus SHROOM2_S1297 in LSCC, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SHROOM2→partner) and Y-score (partner→SHROOM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SHROOM2_S1297 →	+0.715	+0.910	<.001	<.001	3	9
OV	SHROOM2_S313 →	+0.619	+0.947	.009	.002	2	9
OV	SHROOM2_S413 →	+1.002	+1.038	<.001	<.001	3	8
COAD	SHROOM2_S779 →	+1.016	+1.107	<.001	<.001	3	8
BRCA	SHROOM2_S922 →	+1.050	+0.928	<.001	<.001	3	8
LSCC	SHROOM2_S1039 →	+0.692	+0.853	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,233 associations by consensus.

SHROOM2 vs SHROOM2_S1297 — LSCC

Explore this scatter interactively →