SHOC1

Across TCGA cell cohorts, SHOC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,678 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SHOC1-associated GO terms across cancer lineages are Post-transcriptional gene silencing, miRNA processing, and Regulatory ncRNA processing. Each is linked with SHOC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SHOC1-to-partner and partner-to-SHOC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-transcriptional gene silencing grouped by SHOC1-low versus SHOC1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHOC1→partner) and Y-score (partner→SHOC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Post-transcriptional gene silencing →	+0.082	+0.736	.004	.005	2	7
PANCREAS	miRNA processing →	+0.079	+0.506	<.001	.003	3	6
PANCREAS	Regulatory ncRNA processing →	+0.071	+0.572	<.001	.001	3	6
SOFT_TISSUE	Regulatory ncRNA-mediated gene silencing →	+0.049	+0.254	.003	.005	3	6
CNS	Regulation of protein modification by small protein conjugation or removal →	+0.038	+0.491	.001	.008	3	6
SKIN	Positive regulation of tumor necrosis factor-mediated signaling pathway →	+0.126	+0.335	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,678 associations by consensus.

Post-transcriptional gene silencing by SHOC1 expression — OESOPHAGUS

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