Across TCGA patient cohorts, SHMT1P1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,741 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SHMT1P1-associated proteins across cancer lineages are DHX9, DIDO1_S523, and HNRNPK. Each is linked with SHMT1P1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SHMT1P1-to-partner and partner-to-SHMT1P1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SHMT1P1→partner) and Y-score (partner→SHMT1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DHX9 →	+0.330	+0.815	<.001	<.001	3	5
OV	DIDO1_S523 →	+0.696	+0.415	.004	.001	3	4
GBM	HNRNPK →	+0.314	+0.754	<.001	<.001	3	4
LSCC	SRSF9 →	+0.502	+1.003	<.001	<.001	3	3
PDAC	THOC2_T1443 →	+0.441	+0.293	<.001	<.001	3	3
GBM	TRAPPC9 →	-0.171	-0.481	.004	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,741 associations by consensus.

Exploration

SHMT1P1 survival (RNA) · tumor vs normal (RNA) · all SHMT1P1 data types