SHLD1

Across TCGA patient cohorts, SHLD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,663 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SHLD1-associated proteins across cancer lineages are RBBP9, TRMT6, and NSFL1C. Each is linked with SHLD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SHLD1-to-partner and partner-to-SHLD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SHLD1 versus RBBP9 in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SHLD1→partner) and Y-score (partner→SHLD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RBBP9 →	+0.480	+0.556	<.001	<.001	3	6
COAD	TRMT6 →	+0.393	+0.887	<.001	<.001	3	6
OV	NSFL1C →	+0.514	+0.657	.001	.003	3	6
UCEC	GPCPD1 →	+0.557	+0.647	<.001	<.001	3	5
COAD	MAVS →	+0.302	+0.720	<.001	<.001	3	5
OV	PTPRA →	+0.344	+0.614	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,663 associations by consensus.

SHLD1 vs RBBP9 — OV

Explore this scatter interactively →